Antimicrobial de-escalation is part of appropriate antibiotic usage in ICU

Appropriate Treatment of Invasive Candidiasis in ICU: Timing, Colonization Index, Candida Score & Biomarkers, Towards de-Escalation?

Turk J Anaesthesiol Reanim 2016; 44: 279-82 DOI: 10.5152/TJAR.2016.0011 ©Copyright 2016 by Turkish Anaesthesiology and Intensive Care Society Available online at www.jtaics.org Appropriate Treatment of Invasive Candidiasis in ICU: Timing, Colonization Index, Candida Score & Biomarkers, Towards deEscalation? Francesco Giuseppe De Rosa1*, Silvia Corcione1*, Giorgia Montrucchio2, Luca Brazzi2, Gio...

Importance of appropriate initial antibiotic therapy and de-escalation in the treatment of nosocomial pneumonia

Inappropriate initial antibiotic therapy in nosocomial pneumonia is associated with higher mortality, longer hospital stays and increased healthcare costs. The key pathogens associated with these adverse outcomes include Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus and Acinetobacter baumannii. Due to the increasing rates of resistance, a new paradigm is needed for treatin...

Does enhanced antibiotic de-escalation really have no benefit in the ICU?

In a recent issue of Critical Care, we read with interest the article by Trupka et al. [1], who investigated the utility of an enhanced antimicrobial de-escalation (EAD) program in mechanically ventilated patients with suspected pneumonia. They found that the EAD program did not affect the rate of antibiotic de-escalation or the duration of antibiotic therapy in intensive care units (ICUs). We ...

De-escalation and Streamlining of Antimicrobial Therapy

24. ANKeM ANTİBİYOTİK Ve KeMOTeRAPİ KONGResİ, ÖlÜDeNİZ-FeThİYe, 29 NİsAN 03 MAYIs 2009 Prolonged administration of a broad spectrum antibiotic has important ecologic consequences. A comparison of two empirical antibiotic policies with a different spectrum in a neonatal ward has demonstrated that the combination of cefotaxime with amoxicillin favoured the selection of resistant Enterobacter stra...

Antimicrobial Stewardship Program Intervention Package for Increasing Appropriate Outpatient Antibiotic Usage: A Clinic-Feedback Based Approach